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Fencer Vulns
high 8.4

CVE-2026-17583 json

Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity Check

published 2026-08-05 3 mo ago modified 2026-08-26 2 mo ago also EUVD-2026-53616

cvss
8.4
version 3.1, CNA
cisa kev
Not listed
not in CISA's catalog
epss
0.1%
EPSS 0.1% chance of exploitation in 30 days, percentile 3%
public exploits
0
none known

Summary

The affected

Thermo Fisher Applied Biosystems Genetic Analyzers are vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.

Patch / fix

  • thermofisher applied_biosystems_3500/3500xl_series_data_collection_software 4.0.3
  • thermofisher applied_biosystems_3730/3730xl_series_data_collection_software 5.0.3
  • thermofisher applied_biosystems_seqstudio_flex_series_instrument_software 1.2.1
  • thermofisher applied_biosystems_seqstudio_genetic_analyzer_data_collection_software 1.2.6
  • thermofisher genemapper_id-x 1.7.4

Vendor advisories

What the vendors themselves say about their products: affected, fixed or not affected, and what to do.

cisa ICSMA-26-216-01 updated cvss 8.4

Thermo Fisher Applied Biosystems Genetic Analyzers

  • Thermo Fisher ABI PRISM 310 Data Collection Software <=3.1 Thermo Fisher ABI PRISM 3100/3100-Avant Data Collection Software <=2.0 Thermo Fisher Applied Biosystems 3130 Series Data Collection Software <=4.1
    affected: vendor fix, mitigation “Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).” documents.thermofisher.com
  • Thermo Fisher Applied Biosystems 3500/3500xL Series Data Collection Software <=4.0.2
    affected: fixed in 4.0.3, mitigation “Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).” downloads.thermofisher.com
  • Thermo Fisher Applied Biosystems 3730/3730xL Series Data Collection Software <=5.0.2
    affected: fixed in 5.0.3, mitigation “Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).” downloads.thermofisher.com
  • Thermo Fisher Applied Biosystems GeneMapper ID-X Software <=v1.7.3
    affected: fixed in 1.7.4, mitigation “Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).” downloads.thermofisher.com
  • Thermo Fisher Applied Biosystems SeqStudio Flex Series Instrument Software <=1.2.0
    affected: fixed in 1.2.1, mitigation “Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).” downloads.thermofisher.com
  • Thermo Fisher Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software <=1.2.5
    affected: fixed in 1.2.6, mitigation “Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).” downloads.thermofisher.com

From CISA ICS and IT advisories (CSAF, https://github.com/cisagov/CSAF), a U.S. Government work; changed: reduced to products, statuses and remediations. CISA notification · csaf

CISA SSVC

Exploitation
none
Automatable
no
Technical impact
total
Assessed
3 mo ago

Exploit prediction

0.14% chance of exploitation in the next 30 days, higher than 3% of all scored CVEs (FIRST EPSS, 2026-11-08).

CVSS scores

assigned by version score vector
CNA 3.1 8.4 CVSS:3.1/AV:L/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H
CNA 4.0 8.3 CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:N/VC:N/VI:H/VA:H/SC:N/SI:H/SA:N
CNA 4.0 8.3 CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:N/VC:N/VI:H/VA:H/SC:N/SI:H/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X

Affected products

  • Thermo Fisher Applied Biosystems 3500/3500xL Series Data Collection Software
  • Thermo Fisher Applied Biosystems 3730/3730xL Series Data Collection Software
  • Thermo Fisher Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software
  • Thermo Fisher Applied Biosystems SeqStudio Flex Series Instrument Software
  • Thermo Fisher Applied Biosystems GeneMapper ID-X Software
  • Thermo Fisher Applied Biosystems 3130 Series Data Collection Software
  • Thermo Fisher ABI PRISM 3100/3100-Avant Data Collection Software
  • Thermo Fisher ABI PRISM 310 Data Collection Software

Classification

Weakness
  • CWE-353 Missing Support for Integrity Check

References

Sources

Fencer Vulns keeps one entry per vulnerability: the CVE id wins, then GHSA, and records that alias each other are merged, except that two CVEs always keep separate entries. The same data is available as JSON.