GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory.

published 2025-08-07 15 mo ago modified 2026-06-17 4 mo ago also EUVD-2025-23937

cvss: 7.8; version 3.1, CNA
cisa kev: Not listed; not in CISA's catalog
epss: 0.3%; EPSS 0.3% chance of exploitation in 30 days, percentile 18%
public exploits: 0; none known

GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The directory is accessible with full read, write, and execute permissions for all users, allowing unprivileged users to manipulate files within the directory, including executable files like GPMAW3.exe, Fragment.exe, and the uninstaller GPsetup64_17028.exe. An attacker with user-level access can exploit this misconfiguration by replacing or modifying the uninstaller (GPsetup64_17028.exe) with a malicious version. While the application itself runs in the user's context, the uninstaller is typically executed with administrative privileges when an administrator attempts to uninstall the software. By exploiting this flaw, an attacker could gain administrative privileges and execute arbitrary code in the context of the admin, resulting in privilege escalation.

CISA SSVC

Exploitation: Proof of concept is public
Automatable: no
Technical impact: total
Assessed: 15 mo ago (2025-08-08)

Exploit prediction

0.26% chance of exploitation in the next 30 days, higher than 18% of all scored CVEs (FIRST EPSS, 2026-11-08).

Exploits and checks

github.com https://github.com/LukeSec/CVE-2025-50675-GPMAW-Permissions/tree/main referenced PoC, tagged "exploit" by a source, unverified

CVSS scores

assigned by	version	score	vector
CISA ADP	3.1	7.8	CVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
CNA	3.1	7.8	CVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H

Classification

Weakness

CWE-732 Incorrect Permission Assignment for Critical Resource

References

Sources

CVE List CVE-2025-50675
NVD CVE-2025-50675

Fencer Vulns keeps one entry per vulnerability: the CVE id wins, then GHSA, and records that alias each other are merged, except that two CVEs always keep separate entries. The same data is available as JSON.

Summary