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Fencer Vulns
medium 4.3

CVE-2025-12921 json

OpenClinica Community Edition CRF Data Import ImportCRFData xml injection

published 2025-11-09 11 mo ago modified 2026-10-07 32 d ago also EUVD-2025-38721

cvss
4.3
version 3.1, CNA
cisa kev
Not listed
not in CISA's catalog
epss
0.6%
EPSS 0.6% chance of exploitation in 30 days, percentile 47%
public exploits
0
none known

Summary

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

CISA SSVC

Exploitation
Proof of concept is public
Automatable
no
Technical impact
partial
Assessed
11 mo ago

Exploit prediction

0.57% chance of exploitation in the next 30 days, higher than 47% of all scored CVEs (FIRST EPSS, 2026-11-08).

Exploits and checks

  • github.com https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md referenced PoC, tagged "exploit" by a source, unverified
  • github.com https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc referenced PoC, tagged "exploit" by a source, unverified

CVSS scores

assigned by version score vector
CNA 4.0 5.3 CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P
CNA 3.1 4.3 CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N/E:P/RL:X/RC:R
CNA 3.0 4.3 CVSS:3.0/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N/E:P/RL:X/RC:R
CNA 2.0 4.0 AV:N/AC:L/Au:S/C:P/I:N/A:N/E:POC/RL:ND/RC:UR
CNA 4.0 2.1 CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
CNA 3.1 4.3 CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N
NVD 3.1 8.8 CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
CNA 2.0 4.0 AV:N/AC:L/Au:S/C:P/I:N/A:N

Affected products

  • OpenClinica Community Edition

Classification

Weakness
  • CWE-91 XML Injection
  • CWE-74 Improper Neutralization of Special Elements in Output Used by a Downstream Component

References

Sources

Fencer Vulns keeps one entry per vulnerability: the CVE id wins, then GHSA, and records that alias each other are merged, except that two CVEs always keep separate entries. The same data is available as JSON.