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Fencer Vulns
critical 10.0

CVE-2022-1519 json

LRM does not restrict the types of files that can be uploaded to the affected product.

published 2022-06-24 4 y ago modified 2026-06-17 4 mo ago also EUVD-2022-24817

cvss
10.0
version 3.1, CNA
cisa kev
Not listed
not in CISA's catalog
epss
1.4%
EPSS 1.4% chance of exploitation in 30 days, percentile 72%
public exploits
0
none known

Summary

LRM does not restrict the types of files that can be uploaded to the affected product. A malicious actor can upload any file type, including executable code that allows for a remote code exploit.

Vendor advisories

What the vendors themselves say about their products: affected, fixed or not affected, and what to do.

cisa ICSA-22-153-02 updated cvss 10.0

Illumina Local Run Manager

  • Illumina iSeq 100 Instrument LRM >= 1.3, <= 3.1 Illumina MiniSeq Instrument LRM >= 1.3, <= 3.1 Illumina MiSeq Dx LRM >= 1.3, <= 3.1 Illumina MiSeq Instrument LRM >= 1.3, <= 3.1 Illumina NextSeq 500 Instrument LRM >= 1.3, <= 3.1 Illumina NextSeq 550 Instrument LRM >= 1.3, <= 3.1
    +1 more products
    Illumina NextSeq 550Dx LRM >= 1.3, <= 3.1
    affected: mitigation “For instruments connected to the Internet, the software patch is available for download.” support.illumina.com

From CISA ICS and IT advisories (CSAF, https://github.com/cisagov/CSAF), a U.S. Government work; changed: reduced to products, statuses and remediations. CISA notification · csaf

CISA SSVC

Exploitation
none
Automatable
yes
Technical impact
total
Assessed
18 mo ago

Exploit prediction

1.40% chance of exploitation in the next 30 days, higher than 72% of all scored CVEs (FIRST EPSS, 2026-11-08).

CVSS scores

assigned by version score vector
CNA 3.1 10.0 CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:C/C:H/I:H/A:H
NVD 3.1 9.8 CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H
NVD 2.0 10.0 AV:N/AC:L/Au:N/C:C/I:C/A:C

Affected products

  • Illumina NextSeq 550Dx
  • Illumina MiSeq Dx
  • Illumina NextSeq 500 Instrument
  • Illumina NextSeq 550 Instrument
  • Illumina MiSeq Instrument
  • Illumina iSeq 100 Instrument
  • Illumina MiniSeq Instrument

Classification

Weakness
  • CWE-434 Unrestricted Upload of File with Dangerous Type

References

Sources

Fencer Vulns keeps one entry per vulnerability: the CVE id wins, then GHSA, and records that alias each other are merged, except that two CVEs always keep separate entries. The same data is available as JSON.